Lignans from Phyllanthus niruri L. and Their Antifusarium Properties

نویسندگان

چکیده

In this study, two lignan compounds were isolated from acetone extract of Phyllanthus niruri L. nirtetralin B (1) and phyllanthin (2) using several chromatographic methods followed by molecular structure elucidation mainly based on 1D 2D 1H 13C NMR spectrum. The tested for their antimicrobial properties against the plant pathogenic fungus, Fusarium oxysporum, agar plate well diffusion method. microdilution method determined minimum inhibitory concentration (MIC) fungicide (MFC). addition, microconidia germination inhibition test was carried out As a result, compound 1 had MIC MFC values 4 16 μg/mL, respectively. While 2 showed same μg/mL. Further testing F. oxysporum that inhibited 100% at × MIC. comparison, only able to inhibit 29%. This study revealed is potential new derived local medicinal plants. However, further research needed identify interaction mechanism between fungal pathogen develop antifungal agents.

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ژورنال

عنوان ژورنال: Jurnal kimia Valensi

سال: 2022

ISSN: ['2460-6065', '2548-3013']

DOI: https://doi.org/10.15408/jkv.v8i2.25057